Frontiers | Comparing the Hinge-Type Mobility of Natural and Designed Intermolecular Bi-disulfide Domains
Two Families of Hinges IgG-based hinges, derived from IgG1, IgG2, or... | Download Scientific Diagram
Human IgG4: a structural perspective - Davies - 2015 - Immunological Reviews - Wiley Online Library
An exploratory universal LC–MS/MS assay for bioanalysis of hinge region-stabilized human IgG4 mAbs in clinical studies | Bioanalysis
Prevention of Fab-arm exchange and antibody reduction via stabilization of the IgG4 hinge region
L445P mutation on heavy chain stabilizes IgG4 under acidic conditions
Fc-Fc interactions of human IgG4 require dissociation of heavy chains and are formed predominantly by the intra-chain hinge isomer. | Semantic Scholar
Pre-existing Reactivity to an IgG4 Fc-Epitope: Characterization and Mitigation of Interference in a Bridging Anti-drug Antibody Assay | SpringerLink
Frontiers | The Role of IgG4 in Autoimmunity and Rheumatic Diseases
Hinge-deleted IgG4 blocker therapy for acetylcholine receptor myasthenia gravis in rhesus monkeys | Scientific Reports
Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo | Nature Biotechnology
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Antibodies | Free Full-Text | Taking the Hinge off: An Approach to Effector-Less Monoclonal Antibodies
Immunoglobulin G (IgG)- Structure, Subclasses and Functions
Impact of Molecular Processing in the Hinge Region of Therapeutic IgG4 Antibodies on Disposition Profiles in Cynomolgus Monkeys | Drug Metabolism & Disposition
A Mass‐Spectrometry‐Based Modelling Workflow for Accurate Prediction of IgG Antibody Conformations in the Gas Phase - Hansen - 2018 - Angewandte Chemie International Edition - Wiley Online Library
Structural characteristics of investigated IgG subclasses. A:... | Download Scientific Diagram
Antibodies | Free Full-Text | Taking the Hinge off: An Approach to Effector-Less Monoclonal Antibodies
Two Families of Hinges IgG-based hinges, derived from IgG1, IgG2, or... | Download Scientific Diagram
Characteristics of IgG4: structure of IgG4 antibody (A); Fab-arm... | Download Scientific Diagram
Domain structures of human IgG1 and IgG4. (A) Each heavy chain of IgG1... | Download Scientific Diagram
Is it bad, is it good, or is IgG4 just misunderstood? | Science Immunology
Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange | PNAS
An exploratory universal LC–MS/MS assay for bioanalysis of hinge region-stabilized human IgG4 mAbs in clinical studies | Bioanalysis
Enlarging the repertoire of therapeutic monoclonal antibodies platforms: domesticating half molecule exchange to produce stable IgG4 and IgG1 bispecific antibodies - ScienceDirect
